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This calculator is provided as a reference tool for research purposes only. Always follow your institution’s safety protocols when handling research compounds.
Epitalon 10mg is a synthetic research peptide studied in relation to pineal peptide research, telomere biology models, telomerase pathway research, circadian rhythm research, melatonin-related pathway models and cellular ageing research contexts.
Epitalon is also commonly written as Epithalon or Epithalone. PubChem lists Epitalon with the molecular formula C14H22N4O9 and molecular weight of approximately 390.35 g/mol.
A 2025 review describes Epitalon as the tetrapeptide Ala-Glu-Asp-Gly, also known as AEDG, and explains that it was synthesised based on the amino acid composition of Epithalamin, a bovine pineal gland extract.
This product is supplied for laboratory research use only. It is not a medicine, supplement, sleep product, anti-ageing product, longevity product, hormone product, melatonin product, wellness product or injectable product for human use.
| Product Detail | Information |
|---|---|
| Product name | Epitalon |
| Common research names | Epitalon, Epithalon, Epithalone, AEDG |
| Size | 10mg |
| Product type | Research peptide |
| Research category | Pineal Peptide Research / Telomere Biology Research |
| Common research interest | Telomerase, telomere biology, pineal peptide research, circadian pathway models and cellular ageing research |
| Peptide type | Synthetic tetrapeptide |
| Common sequence | Ala-Glu-Asp-Gly |
| Short sequence | AEDG |
| Molecular formula | C14H22N4O9 |
| Molecular weight | Approximately 390.35 g/mol |
| Form | Lyophilised powder |
| Intended use | Laboratory research only |
| Human use | Not for human consumption, administration, sleep, anti-ageing, longevity or injection |
| Documentation | Certificate of Analysis should be checked before use |
| Component | Research Class | General Research Role |
| Epitalon | Synthetic tetrapeptide | Studied in pineal peptide, telomere and cellular ageing pathway research |
| Alanine | Amino acid component | Forms the “A” in AEDG |
| Glutamic acid | Amino acid component | Forms the “E” in AEDG |
| Aspartic acid | Amino acid component | Forms the “D” in AEDG |
| Glycine | Amino acid component | Forms the “G” in AEDG |
| AEDG sequence | Tetrapeptide sequence | Common shorthand used in Epitalon literature |
| Molecular formula | C14H22N4O9 | Listed by PubChem for Epitalon |
| Lyophilised peptide preparation | Freeze-dried peptide format | Supports stability before reconstitution when stored correctly |
Product identity, sequence, purity, salt form, acetate status and batch information should always be confirmed through supplier documentation and the Certificate of Analysis. Researchers should not rely on product name alone when confirming peptide identity.
Epitalon is studied as a short pineal tetrapeptide research compound. In laboratory and preclinical research settings, it is commonly examined in relation to telomerase activity, telomere biology, pineal peptide signalling, melatonin-related pathway models, circadian rhythm research and gene regulation models.
Research literature has discussed Epitalon in relation to telomerase activity and telomere-length models. A 2003 paper reported that Epithalon exposure in telomerase-negative human fetal fibroblast culture induced catalytic telomerase subunit expression, telomerase activity and telomere elongation.
Epitalon has also been studied in pineal and circadian research contexts. A PubMed-indexed study in aged monkeys reported changes in melatonin synthesis and cortisol rhythm after Epitalon exposure, although this is animal research context and must not be turned into a sleep, hormone or anti-ageing claim for a research-use product.
| Research Area | Epitalon |
| Main research category | Pineal tetrapeptide research |
| Common shorthand | AEDG |
| Sequence | Ala-Glu-Asp-Gly |
| Peptide length | Four amino acids |
| Telomere research interest | Telomerase and telomere-length pathway models |
| Pineal research interest | Pineal peptide and melatonin-related pathway research |
| Circadian research interest | Circadian rhythm and endocrine timing models |
| Cellular ageing research interest | Cell-cycle, senescence and gene expression pathway models |
| Evidence limitation | Mostly laboratory, animal, preclinical and limited regional research contexts |
| Product limitation | Research use only, not approved for human use |
| Feature | Epitalon | Epithalamin |
| Research class | Synthetic tetrapeptide | Pineal gland peptide extract |
| Common sequence | Ala-Glu-Asp-Gly / AEDG | Mixture or extract-based preparation |
| Product identity | Defined short peptide | More complex extract context |
| Common research focus | Telomerase, telomere, pineal and circadian pathway research | Pineal extract and ageing-related research contexts |
| Product verification | Sequence and purity confirmed by CoA | Extract identity and composition are more complex |
| Human-use claim | Not appropriate for research-use products | Not appropriate for research-use products |
| Feature | Epitalon | Pinealon |
| Research class | Pineal tetrapeptide research peptide | Short peptide bioregulator research compound |
| Common sequence | Ala-Glu-Asp-Gly | Glu-Asp-Arg |
| Main research interest | Telomerase, pineal and circadian pathway research | Neuroprotection and gene expression research contexts |
| Common SEO risk | Anti-ageing, longevity and sleep claims | Brain support, neuroprotection and anti-ageing claims |
| Safer positioning | AEDG pineal tetrapeptide research | Short peptide gene regulation research |
| Human-use claim | Not appropriate | Not appropriate |
| Feature | Epitalon | NAD+ |
| Research class | Synthetic tetrapeptide | Nucleotide coenzyme research compound |
| Main pathway interest | Telomerase, pineal and circadian pathway research | NAD+/NADH redox balance, sirtuins and PARP pathway research |
| Common ageing-related context | Cellular ageing and telomere biology research | Cellular metabolism and redox ageing pathway research |
| Common SEO risk | Longevity, anti-ageing and sleep claims | Energy, anti-ageing and infusion claims |
| Safer positioning | Pineal tetrapeptide research peptide | NAD+ redox research compound |
| Human-use claim | Not appropriate | Not appropriate |
| Product | Safer Research Positioning |
| Epitalon 10mg | AEDG, pineal tetrapeptide, telomerase and circadian pathway research |
| NAD+ 500mg | NAD+/NADH redox, sirtuin, PARP and mitochondrial pathway research |
| SS-31 10mg | Cardiolipin and inner mitochondrial membrane research |
| MOTS-C 10mg | Mitochondrial-derived peptide and AMPK pathway research |
| Glutathione 1500mg | GSH redox and oxidative stress pathway research |
These products should not be written as if they are interchangeable. Epitalon is best positioned around AEDG, pineal peptide, telomerase and circadian pathway research, not general anti-ageing, longevity, sleep or wellness use.
| Common Online Claim | Safer Research-Use Wording |
| Anti-ageing | Studied in cellular ageing and telomere biology research models |
| Longevity | Better framed as lifespan-related preclinical research context, not a human benefit claim |
| Telomere extension | Better framed as telomerase and telomere-length pathway research |
| Better sleep | Better framed as circadian and melatonin-related pathway research |
| Melatonin boost | Better framed as pineal peptide and melatonin pathway research |
| Immune support | Not an approved or appropriate product claim |
| Hormone balance | Better framed as endocrine timing and circadian pathway models |
| Wellness | Not suitable for research-use product positioning |
Epitalon 10mg is not intended to diagnose, treat, cure or prevent any disease. It is not supplied for anti-ageing, longevity, sleep improvement, melatonin support, hormone regulation, immune support, fatigue, recovery, brain health, lifespan extension, wellness, cosmetic use, injection or therapeutic use.
All information on this page is provided for laboratory research and product handling context only.
There is no universal recommended dilution for Epitalon 10mg. Dilution depends on the research protocol, required working concentration, assay design, solvent compatibility, salt form, storage method and validated laboratory procedure.
For research concentration planning only, the basic formula is:
Total peptide amount divided by diluent volume equals final concentration.
| Diluent Added to 10mg Vial | Final Concentration |
| 1mL | 10mg/mL |
| 2mL | 5mg/mL |
| 2.5mL | 4mg/mL |
| 3mL | 3.33mg/mL |
| 4mL | 2.5mg/mL |
| 5mL | 2mg/mL |
| 10mL | 1mg/mL |
These are research concentration examples only. They are not human dosing instructions and must not be used to calculate injection quantities, treatment quantities or administration schedules.
Before handling Epitalon 10mg in a laboratory setting, make sure all materials, documentation and clean handling conditions are prepared.
| Item | Purpose |
| Product vial | Contains lyophilised Epitalon peptide |
| Certificate of Analysis | Confirms batch-level testing information |
| Sequence or identity confirmation | Helps confirm the product is Epitalon / AEDG |
| Suitable research-grade diluent | Used to prepare a working research solution |
| Sterile lab consumables | Helps reduce contamination risk |
| Personal protective equipment | Gloves, lab coat and eye protection |
| Alcohol wipes or approved disinfectant | Used for surface and vial-top preparation |
| Laboratory labels | Records concentration, date, batch and handler details |
| Cold storage access | Supports correct storage after preparation |
| Disposal container | Used for compliant laboratory waste disposal |
The following is a general laboratory handling framework only. Always follow the product Certificate of Analysis, supplier documentation, SDS, institutional procedures and validated research protocol.
Check the product label, batch number, Certificate of Analysis, peptide identity, AEDG sequence and storage requirements before handling the vial.
Use a clean laboratory workspace. Wear appropriate PPE and disinfect the bench surface, vial top and any required equipment.
If the vial has been stored cold, allow it to equilibrate according to laboratory procedure before opening or reconstitution. Avoid condensation entering the vial.
Add the selected research-grade diluent slowly down the inside wall of the vial. Avoid forceful spraying directly onto the lyophilised powder.
Gently swirl or roll the vial until the powder is dissolved. Avoid aggressive shaking, unnecessary vortexing or foaming unless a validated protocol specifically allows it.
Check the solution for cloudiness, visible particles, unusual colour changes or undissolved material. If anything appears abnormal, quarantine the vial and check supplier documentation.
Label the vial or aliquots with the product name, concentration, diluent used, date prepared, batch number and researcher initials.
Place the reconstituted solution into the required storage condition as soon as possible. Avoid unnecessary warming, cooling or repeated freeze-thaw cycles.
Some lyophilised peptide products may take time to fully hydrate. Dissolution should always be handled gently and according to laboratory protocol.
| Issue | What It May Indicate | Safer Response |
| Powder clinging to vial wall | Static or lyophilisation residue | Allow more contact time with diluent |
| Small particles remain | Incomplete hydration | Continue gentle swirling |
| Cloudy solution | Possible incompatibility or contamination | Stop and check documentation |
| Foaming | Too much agitation | Let the solution settle and avoid shaking |
| Colour change | Possible degradation or contamination | Do not continue without supplier guidance |
| Product identity unclear | Possible peptide mix-up | Stop and confirm CoA before using |
| Storage Factor | Guidance |
| Product form | Lyophilised powder |
| Storage condition | Follow supplier label and Certificate of Analysis |
| Light exposure | Protect from unnecessary light exposure |
| Moisture exposure | Keep sealed until use |
| Temperature changes | Avoid repeated temperature cycling |
| Handling | Minimise unnecessary opening or vial puncture |
| Variant control | Store and label separately from NAD+, SS-31, MOTS-C and other cellular ageing research products |
| Storage Factor | Guidance |
| Storage condition | Follow validated research protocol |
| Labelling | Record product name, concentration, date, diluent and batch number |
| Sequence tracking | Record Epitalon / AEDG identity where documented |
| Freeze-thaw cycles | Avoid repeated freeze-thaw exposure |
| Aliquoting | Use small research aliquots where appropriate |
| Contamination control | Use clean laboratory technique |
| Light exposure | Protect from unnecessary light exposure where required |
| Disposal | Dispose according to laboratory waste procedures |
Peptides may be sensitive to temperature, light, pH, agitation and contamination. Storage conditions should be confirmed through supplier documentation or the laboratory’s validated method.
This page does not provide human dosing, injection instructions, injection schedules, cycle instructions, sleep-use instructions, anti-ageing protocols or administration guidance.
Epitalon 10mg is not supplied for human or animal administration. It is a laboratory research-use product only.
For research settings, any measured aliquots should be prepared according to the concentration required by the approved research protocol. All calculations should be checked, documented and traceable.
| Planning Item | What to Record |
| Final concentration | Total peptide amount and diluent volume |
| Working solution | Concentration used in the research protocol |
| Aliquot volume | Volume transferred into each labelled lab tube |
| Batch details | Product batch, CoA and preparation date |
| Peptide identity | Confirmation that the product is Epitalon / Epithalon |
| Sequence confirmation | Ala-Glu-Asp-Gly / AEDG where documented |
| Salt form | Supplier-specific salt form or acetate status, where documented |
| Storage location | Fridge, freezer or other controlled storage area |
| Handler details | Researcher name or initials |
| Preparation date | Date and time of reconstitution |
| Disposal date | When the aliquot should no longer be used |
| Strength check | Confirmation that the 10mg vial strength matches the approved research protocol |
| Compliance check | Confirmation that no anti-ageing, longevity, sleep or injection wording is attached to the material |
Correct handling is important for research consistency, contamination control and product traceability. Most mistakes occur when products are not labelled clearly, concentration calculations are not recorded, storage conditions are not followed or human anti-ageing claims are mixed into research-use product pages.
Because Epitalon is commonly discussed online in relation to anti-ageing, longevity, telomeres, sleep and melatonin, product pages should avoid wording that could be interpreted as encouraging human self-use, injection, hormone manipulation, sleep treatment or lifespan-extension use.
| Always | Why It Matters |
| Check the Certificate of Analysis | Confirms batch-level information |
| Confirm peptide identity | Helps verify the product is Epitalon / AEDG |
| Confirm sequence where documented | Supports accurate product identification |
| Confirm salt form where documented | Supports correct research calculations |
| Use PPE | Reduces contamination and exposure risk |
| Label every vial and aliquot | Prevents mix-ups |
| Record concentration calculations | Supports traceability |
| Use clean laboratory technique | Reduces contamination risk |
| Follow institutional protocols | Keeps handling consistent and auditable |
| Store according to documentation | Helps protect peptide integrity |
| Dispose of lab waste correctly | Supports safety and compliance |
| Use research-use wording only | Reduces misleading human-use interpretation |
| Keep telomerase research separate from human benefit claims | Avoids unsafe anti-ageing or longevity positioning |
| Never | Why It Is Risky |
| Never use for self-injection | Product is research use only |
| Never sell or promote as an anti-ageing product | Creates human-use and compliance risk |
| Never make longevity or lifespan claims | Not an approved or appropriate product claim |
| Never make sleep or melatonin claims | Not suitable for a research-use product page |
| Never market as hormone regulation | Creates misleading human-use interpretation |
| Never make immune support or wellness claims | Not an approved or appropriate product claim |
| Never imply telomerase research equals human anti-ageing benefit | Research pathway context is not a product-use claim |
| Never copy cycle instructions from social media | They may be unsafe, inaccurate or non-compliant |
| Never assume purity without CoA | Batch quality must be documented |
| Never use a damaged or unlabelled vial | Identity and sterility may be uncertain |
| Never shake aggressively | May affect peptide integrity |
| Never use random solvents | May damage the peptide or alter research results |
| Never leave reconstituted product unlabelled | Creates traceability risk |
The table below is for concentration planning only. It does not represent dosage, injection quantity, treatment quantity or recommended administration.
| Total Vial Amount | Diluent Volume | Final Concentration |
| 10mg | 1mL | 10mg/mL |
| 10mg | 2mL | 5mg/mL |
| 10mg | 2.5mL | 4mg/mL |
| 10mg | 3mL | 3.33mg/mL |
| 10mg | 4mL | 2.5mg/mL |
| 10mg | 5mL | 2mg/mL |
| 10mg | 10mL | 1mg/mL |
If a researcher adds 2mL of suitable research-grade diluent to a 10mg vial, the resulting concentration is 5mg/mL.
This calculation is for research concentration planning only. It is not a human or animal dosing example, treatment example, injection example, cycle example or administration instruction.
Epitalon is a synthetic tetrapeptide research compound also known as Epithalon, Epithalone or AEDG. It is commonly studied in relation to pineal peptide research, telomerase pathway models, telomere biology, circadian pathway research and cellular ageing models.
Yes. Epitalon is a tetrapeptide, meaning it contains four amino acids. Its common sequence is Ala-Glu-Asp-Gly, also written as AEDG.
Epitalon is commonly studied in relation to telomerase activity, telomere biology, pineal peptide signalling, melatonin-related pathway models and circadian rhythm research.
No. This research product is not approved or supplied for anti-ageing, longevity, lifespan extension, sleep, melatonin support, wellness, hormone regulation, injection or human administration. It should be described only as a laboratory research product.
No. Epitalon is a synthetic tetrapeptide, while Epithalamin refers to a pineal peptide extract context. The two should not be treated as identical products.
No. Epitalon is a synthetic tetrapeptide studied in pineal and telomere pathway research. NAD+ is a nucleotide coenzyme studied in redox, sirtuin, PARP and cellular metabolism research.
Telomerase and telomere research is a laboratory pathway context. It should not be turned into a claim that a research-use product reverses ageing, extends lifespan, improves sleep or provides human health benefits.
A Certificate of Analysis provides batch-level testing information. It helps researchers verify product identity, purity, salt form, sequence and quality documentation before use in a research setting.
| Resource | Why It Is Useful |
| PubChem Epitalon compound profile | Useful background on Epitalon identity, molecular formula and molecular weight. |
| Epitalon pineal tetrapeptide review | Useful background on Epitalon as AEDG, its Epithalamin context and research areas across in vitro, in vivo and in silico studies. |
Research Use Only: Epitalon 10mg is supplied strictly for laboratory research purposes. It is not intended for human or animal consumption, injection, therapeutic use, cosmetic use, diagnostic use, anti-ageing, longevity, lifespan extension, sleep improvement, melatonin support, hormone regulation, immune support, fatigue, recovery, brain health, wellness, body enhancement or performance enhancement. Information on this page is provided for research education and product handling context only. Always follow applicable laws, institutional procedures, supplier documentation, SDS guidance and qualified laboratory protocols.
